Mankhwala a Medium-Chain Triglycerides (MCT) | Lipophilic solvent & Mankhwala Omwe Amaperekedwa Pakamwa/Pakamwa/Obayidwa Jakisoni | USP/EP/ChP

Medium-Chain Triglycerides (MCT) yathu ndi mankhwala oyeretsera kwambiri omwe amapangidwa ndi triglycerides ya saturated caprylic (C8) ndi capric (C10) fatty acids, yochokera ku mafuta a kokonati ndi kanjedza.Amaoneka ngati mafuta owoneka bwino, opanda mtundu mpaka achikasu pang'ono, otsika kukhuthala komanso onunkhira bwino komanso kukoma kosagwirizana ndi chilengedwe.MCT imagwira ntchito ngati chosungunulira chabwino kwambiri cha mankhwala ochepetsa mafuta m'thupi, chonyamulira mankhwala kuti azitha kupezeka mosavuta, chotsitsimula bwino pakupanga mankhwala opaka pakhungu, komanso chowonjezera kufalikira kwa khungu.Imapereka kukhazikika kwabwino kwa okosijeni, kuyamwa mwachangu (kuzungulira mwachindunji popanda mchere wa bile), komanso imagwirizana bwino ndi ma API ndi zinthu zina zowonjezera.Zimagwirizana ndi mankhwala a USP-NF, EP, JP, ndi ChP okhala ndi CDE registration F20220000316Yoyenera kumwa mankhwala/makapisozi, mafuta odzola pakhungu, zakudya zopatsa thanzi, ndi njira zoperekera mankhwala zodzipangira zokha (SEDDS).

Lumikizanani nafe

Tsatanetsatane wa Zamalonda

Mankhwala a Medium-Chain Triglycerides (MCT)

Chidule cha Zamalonda

Medium-Chain Triglycerides (MCT) ndi mankhwala odziwika bwino omwe amapangidwa ndi chisakanizo cha triglycerides cha mafuta okhuta, makamaka caprylic acid (C8H16O2, octanoic acid) ndi capric acid (C10H20O2, decanoic acid)Ma triglyceride amenewa amapezeka kuchokera ku mafuta okhazikika omwe amachokera ku gawo lolimba, louma la endosperm ya kokonati (Cocos nucifera L.) kapena kuchokera ku endosperm youma ya oil palm (Elaeis guineensis Jacq.)Mafuta acids amalekanitsidwa ndi mafuta amafuta ndipo amapangidwanso ndi glycerol kuti apange chinthu chomaliza..

Chidziwitso cha Zamalonda:

Dzina la Mankhwala:Triglycerides ya Medium-Chain / Caprylic/Capric Triglyceride
Nambala ya CAS:73398-61-5 (komanso 85409-09-2 kapena 538-24-9)
Nambala Yolembetsa ya CDE:F20220000316
Kutsatira Malamulo a Pharmacopoeia:ChP (CP2020), USP-NF (Medium-Chain Triglycerides), EP (Triglycerides, Medium-Chain), JP (Medium chain fatty acid triglyceride)
Mawu ofanana:Mafuta a MCT, Caprylic/Capric Triglyceride, Glycerides mixed decanoyl ndi octanoyl, Miglyol® 812 ofanana, Labrafac™ CC ofanana
Maonekedwe:Mafuta osakhala ndi utoto mpaka chikasu pang'ono, opanda fungo komanso osakoma kwenikweni
Malo Ozizira:Pafupifupi 0°C

Zinthu Zofunika & Mapindu

1. Makhalidwe Abwino Kwambiri Osungunulira

Chosungunulira chabwino kwambiri cha mankhwala ochepetsa mafuta m'thupi komanso ma API osasungunuka bwino m'madzi
Zimathandizira kusungunuka ndi kukhazikika kwa mankhwala a lipophilic
Zimathandizira kuti mankhwala a Gulu Lachiwiri ndi Lachinayi (BCS classification) azipezeka mosavuta.

2. Kumwa Mofulumira & Kagayidwe kachakudya

Amalowa mwachindunji mu magazi a portal popanda kufunikira kwa mchere wa bile kapena ma enzyme a pancreatic
Imasinthidwa mwachangu kuti ipereke mphamvu mwachangu
Kutumiza mwachangu kwa API ku kayendedwe kazinthu, zomwe zingathandize kuti ntchito iyambe kugwira ntchito bwino

3. Mbiri Yabwino Kwambiri Yokhazikika

Kukana kwambiri okosijeni (mtengo wa ayodini ≤1.0)
Kuchepa kwa mphamvu ya kutentha ndi okosijeni
Imasunga kukhazikika ndi nthawi yosungira mankhwala
Yokhazikika pa kutentha kosiyanasiyana kosungirako (≤25°C imalimbikitsidwa)

4. Katundu Wapamwamba Kwambiri

Kukhuthala:~30 mPa·s pa 20°C (kukhuthala kochepa kuti muzitha kuigwira mosavuta)
Mphamvu Yokoka:0.93-0.96 pa 20°C
Chizindikiro Chowunikira:1.440-1.452 pa 20°C
Kukhuthala kochepa koyenera mitundu yamadzimadzi ndi theka-lolimba

5. Kugwirizana Kwabwino Kwambiri

Imagwirizana ndi ma API osiyanasiyana ndi zinthu zina zowonjezerera mankhwala
Zitha kuphatikizidwa mosavuta mu mitundu yosiyanasiyana popanda mavuto okhudzana ndi kuyanjana
Fungo ndi kukoma kosagwirizana - ndibwino kwambiri pakumwa mankhwala okoma ngati kuli kofunikira kuti munthu amve kukoma

6. Mbiri Yoyang'anira ndi Chitetezo